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Glycine

CAS 56-40-6C2H5NO275.07 g/mol

Glycine is the simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain. It has a role as a neurotransmitter, a micronutrient, a nutraceutical, a hepatoprotective agent, an EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor, a NMDA receptor agonist and a fundamental metabolite. It is a serine family amino acid, an alpha-amino acid and a proteinogenic amino acid. It is a conjugate base of a glycinium. It is a conjugate acid of a glycinate. It is a tautomer of a glycine zwitterion.

IUPAC: 2-aminoacetic acid

Glycine molecular structure

PubChem

Physical & Chemical Properties

Physical and chemical properties
Melting Point451 °F (NTP, 1992)
Density1.1607 (NTP, 1992) - Denser than water; will sink
Solubilitygreater than or equal to 100 mg/mL at 64 °F (NTP, 1992)
Vapor Pressure0.00000013 [mmHg]
pH0.2 molar soln in water: 4.0
AppearanceGlycine appears as white crystals. (NTP, 1992)

Data: PubChem · Last updated: 4/20/2026

GHS Classification

No GHS classification data available.

Classification data is sourced from ECHA.

Regulatory Compliance

TSCA

Listed

note: Status based on EPA TSCA Active Inventory · inventory name: TSCA Chemical Substance Inventory

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SVHC

Not Listed

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FDA GRAS

Not Listed

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HS Code(s): 2922

Data: UN Comtrade

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