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Propylene glycol

CAS 57-55-6C3H8O276.09 g/mol

Propane-1,2-diol is the simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (59C) and high-boiling (188C) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze. It has a role as a protic solvent, an allergen, a mouse metabolite and a human xenobiotic metabolite. It is a glycol and a member of propane-1,2-diols.

IUPAC: propane-1,2-diol

Propylene glycol molecular structure

PubChem

Physical & Chemical Properties

Physical and chemical properties
Melting Point-76 °F (NTP, 1992)
Boiling Point370.8 °F at 760 mmHg (NTP, 1992)
Density1.04 at 68 °F (USCG, 1999) - Denser than water; will sink
Solubilitygreater than or equal to 100 mg/mL at 70 °F (NTP, 1992)
Flash Point210 °F (NTP, 1992)
Vapor Pressure0.08 mmHg at 68 °F ; 0.13 mmHg at 77 °F (NTP, 1992)
AppearanceThick odorless colorless liquid. Mixes with water. (USCG, 1999)

Data: PubChem · Last updated: 4/20/2026

GHS Classification

No GHS classification data available.

Classification data is sourced from ECHA.

Regulatory Compliance

TSCA

Listed

note: Status based on EPA TSCA Active Inventory · inventory name: TSCA Chemical Substance Inventory

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SVHC

Not Listed

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FDA GRAS

Listed

gras notice: Generally Recognized as Safe

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No trade flow data available for this chemical.

HS Code(s): 2905

Data: UN Comtrade

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