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1,3-Butadiene

CAS 106-99-0C4H654.09 g/mol

1,3-Butadiene can cause cancer according to an independent committee of scientific and health experts. It can cause developmental toxicity, female reproductive toxicity and male reproductive toxicity according to The National Institute for Occupational Safety and Health (NIOSH) and The Environmental Protection Agency (EPA).

IUPAC: buta-1,3-diene

1,3-Butadiene molecular structure

PubChem

Physical & Chemical Properties

Physical and chemical properties
Melting Point-164 °F (NTP, 1992)
Boiling Point24.1 °F at 760 mmHg (NTP, 1992)
Density0.621 at 68 °F (USCG, 1999) - Less dense than water; will float
SolubilityInsoluble (NTP, 1992)
Flash Point-105 °F (NTP, 1992)
Vapor Pressure1840 mmHg at 70 °F ; 760 mmHg at 23.9 °F (NTP, 1992)
AppearanceButadiene is a colorless gas with an aromatic odor. It is shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. It is easily ignited. Its vapors are heavier than air and a flame can flash back to the source of leak very easily. It can asphyxiate by the displacement of air. It must be shipped inhibited as butadiene is liable to polymerization. If polymerization occurs in the container, it may violently rupture. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket. It is used to make synthetic rubber and plastics, and to make other chemicals.

Data: PubChem · Last updated: 4/20/2026

GHS Classification

No GHS classification data available.

Classification data is sourced from ECHA.

Regulatory Compliance

TSCA

Listed

note: Status based on EPA TSCA Active Inventory · inventory name: TSCA Chemical Substance Inventory

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SVHC

Not Listed

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FDA GRAS

Not Listed

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No trade flow data available for this chemical.

HS Code(s): 2901

Data: UN Comtrade

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